Dr. Giacomo Rossettini

FSV Fysiek Congres; Back to the Future / Dr. Giacomo Rossettini

Dr. Giacomo Rossettini

Placebo, nocebo and contextual effects in musculoskeletal care: friends or foes?


Giacomo Rossettini werkt momenteel aan de Dipartimento di Neuroscienze, riabilitazione, oftalmologia, genetica e scienze materno-infantili (DINOGMI), aan de Università degli Studi di Genova. Giacomo doet onderzoek in Orthopedische Chirurgie, Sportgeneeskunde en Allied Health Science. Hun meest recente publicatie is ‘Context telt: de psychoneurobiologische determinanten van placebo, nocebo en contextgerelateerde effecten in de fysiotherapie’.



Placebo and nocebo effects are embodied psycho-neurobiological effects capable of producing changes at different neurobiological, body at perceptual and cognitive levels. These modifications are triggered by different Contextual Factors presented in the therapeutic arena. Contextual factors are represented by different healing rituals and signs such as:(a)the clinician’s features;(b)the patient’s features; (c)the patient-clinician relationship; (d)the characteristics of the treatment; and(e)the overall healthcare setting. Contextual Factors have been documented to directly impact musculoskeletal patients’ subjective outcomes (e.g., pain, disability) triggering placebo/nocebo effects: while a positive context can improve therapeutic outcomes by producing placebo effects; a negative context, can a gravate the patients’ clinical conditions by creating nocebo effects. Moving from this premise, this speech aims: (1)to describe the contextual factors as modulators of clinical outcomes in musculoskeletal pain; and (2)to provide guidance for the implementation of contextual factors in clinical practice within the ethical border.





13 Mei